Danny Ings replaces Christian Benteke in the only change to the starting line-up from last weekend's Premier League home game.
Benteke was withdrawn at half time last week with an injury which means he misses out on a return against his old club.
Danny Ings has scored both Liverpool goals in the last two games gets a chance to start alongside Daniel Sturridge.
Despite Bogdan's mid-week heroics, and Mignolet's blunder against Norwich - Simon Mignolet returns to the starting XI.
Liverpool team: Mignolet, Clyne, Skrtel, Sakho, Moreno, Can, Lucas, Milner, Coutinho, Ings, Sturridge.
Substitutes: Bogdan, Toure, Gomez, Lallana, Allen, Origi, Ibe.
— Liverpool FC (@LFC) 26 September 2015
Aston Villa team: Guzan, Amavi, Lescottt, Richards, Hutton, Gana, Westwood, Sanchez, Sinclair, Grealish, Gestede
Subs: Bunn, Clark, Bacuna, Veretout, Ayew, Traore, Gil