4th placed Liverpool host 7th placed Man United in the 8th game of the Premier League season.
At stake for the reds is the possibility of going joint top of the Premier League. For United they will hoping to get back into the top four and keep in touch with the current Premier League leaders.
The reds have won their previous 4 league games, but they have had a 15 day wait due to the international break. Can the reds continue their recent good form?
You can read our final whistle match report here
As it happened...
Dion Dublin, speaking to the BBC, says that United should go for it
I think if Manchester United try to park the bus against Liverpool they will come a cropper.
Liverpool are just too good going forward. United aren't exactly watertight at the back either. For me United have to go for it.
As expected - Wijnaldum misses out due to injury. Lallana only fit enough for the bench.
Emre Can and Daniel Sturridge (making his 100th LFC appearance) start.
Team: Karius, Clyne, Matip, Lovren, Milner, Henderson, Can, Coutinho, Firmino, Mane, Sturridge
Subs: Mignolet, Moreno, Klavan, Lucas, Grujic, Lallana, Origi
No Rooney in the starting line up for United.
De Gea; Valencia, Bailly, Smalling, Blind; Herrera, Pogba, Fellaini; Rashford, Ibrahimovic, Young
Warm ups are over. Players are receiving their final instructions before heading back on to the pitch.
Less than 10 minutes to go now.
Teams are out on to the pitch. Man Utd in their blue away strip. Liverpool wearing the logo of Standard Chartered charity 'Seeing is Believing'.
Mourinho sitting in his seat - Klopp on his feet as YNWA is belted out by the crowd.
Underway at Anfield.
Rashford goes in hard on James Milner. Mourinho waving his hands in the air. Lucky to get away with no yellow card.
Some sloppy passes from Liverpool in these opening minutes. And it doesn't look like Man Utd have come to Anfield to defend either.
Lovren concedes a rather unnecessary free kick outside the box - it's United second free kick of the game. Thankfully comes to nothing.
United have started better tonight.
Another chance for United but Pogba's shot is way off target.
Ibrahimovic gets the ball at the edge of the box allowed to turn and fires on target. Karius saves.
Karius called in to action after Rashford beats Milner and gets a shot in. It's been mostly Manchester United so far in this game. Emre Can really struggling in this game.
LFC's first shot on target. A cross from Henderson but Firmino's header is easily saved by De Gea.
14 fouls committed so far by United, not one yellow card handed out by the Mancunian referee Anthony Taylor.
Liverpool have improved over the past few minutes - first half an hour was dominated by United. Just glimpses of the reds creating some space now in the United half.
Finally the yellow card is produced. Eric Bailly receives it in the 44th minute.
Coutinho's free kick though is disappointing and it's easy for De Gea to collect.
It wasn't pretty at times. Klopp sprints past Mourinho into the tunnel. 0-0.
is underway. Klopp was out early and he looked like he may have had a dressing room rant at the players.
Mix up at the back and Karius passes the ball straight back to United. The ball is fed in and fortunately the offside flag goes up.
Great chance for United. Cross comes in to Zlatan Ibrahimovic but his header at the edge of the 6 yard box isn't on target and it goes back across the goal.
Herrara fouls Coutinho. Free kick for the reds. Played short - comes to nothing.
Big save from David De Gea as Emre Can gets the ball out of his feet and shoots inside the box.
No big surprise. Daniel Sturridge replaced by Adam Lallana. It wasn't a spectacular 100th appearance from Sturridge.
Arrival of Lallana to replace Sturridge seems to have transformed the reds who now look a lot more confident going forward.
Another great save by De Gea - Coutinho drills a shot that the United keeper has to push away. From the resulting corner James Milner goes down injured.
77' Rooney comes on for United - replaces Marcus Rashford.
Liverpool drill the ball across the United area but agonisingly it doesn't arrive at anybody's feet. About 7 minutes left.
Great tackle by Valencia who cleanly takes the ball away from Firmino who was powering towards goal.
Divock Origi on for Roberto Firmino. 85'
Alberto Moreno on for James Milner.
3 minutes injury time coming up.
Liverpool 0-0 Manchester United
Wasn't a classic.
There's no change in the League Table positions but the reds are now 2 points off the top of the table.
Not bad considering last season and we have now played Arsenal, Chelsea, Spurs (away) and 'champions' Leicester and Man Utd at home.
35% possession for Man Utd tonight is their lowest since the stat has been recorded in the Premier League.