The glamour tie of the round is confirmed as the pairing between two sides who hold 14 European Cup titles between them.
5 times Champions Liverpool will take on 9 time Champions Real Madrid over two legs with a place in the Quarter Finals at stake.
Liverpool will travel to the Bernabeu before the return leg at Anfield.
Considering the two sides are European heavyweights they have met in a competitive fixture only once.
1981, the European Cup Final which Liverpool won 1-0 at the Parc des Princes thanks to Alan Kennedy’s 81st minute winner. The reds played twice at the Bernabeu in friendly tournaments against Madrid in 1999 and 2002 – losing on both occasions 2-0.
The full draw is as follows:
Chelsea v Juventus
Villarreal v Panathinaikos
Sporting Lisbon v Bayern Munich
Atletico Madrid v Porto
Lyon v Barcelona
Real Madrid v Liverpool
Arsenal v Roma
Inter Milan v Manchester United
1st leg in Madrid takes place on the 24th or 25th February. Anfield clash two weeks later.