Liverpool will be aiming to complete a league double over Arsenal in a rare Friday night outing for the reds.
The reds will be half-way through the Premier League season when the final whistle sounds, with a win ensuring that the reds will sit inside the top four on Christmas Day.
Arsenal have their own designs on breaking back into the top four and could achieve that if they get the result tonight.
Klopp selects a strong side for the first of four games over the Christmas period.
Emre Can and Sadio Mane return to the line up replacing Oxlade-Chamberlain and Gini Wijnaldum who are on the bench.
As it happened...
Starting eleven: Mignolet, Gomez, Klavan, Lovren, Robertson, Henderson, Can, Coutinho, Mane, Salah, Firmino.
Subs: Karius, Alexander-Arnold, Lallana, Oxlade-Chamberlain, Wijnaldum, Milner, Solanke.
Both Mignolet and Coutinho making their 199th appearance for Liverpool tonight.
Arsene Wenger names the same side that beat Newcastle in their last game.
Arsenal: Cech, Bellerin, Koscielny, Monreal, Maitland-Niles, Wilshere, Xhaka, Iwobi, Ozil, Sanchez, Lacazette.
Subs: Ospina, Walcott, Mustafi, Welbeck, Kolasinac, Coquelin, Elneny.
We mentioned the number 199 earlier and that is precisiely the number of clean sheets goalkeeper Petr Cech has for Arsenal
He is looking for his 200th tonight and hopefully he will still be looking for it when he wakes up tomorrow.
Arsenal fans boo when they hear the name of Alex Oxlade-Chamberlain who is one of LFC's substitutes tonight.
The player had a slow start to his LFC career and many Gunners seemed happy that we had paid them £35M but in recent weeks the England man has looked far more suited to the Liverpool way of playing.
Come on redmen
11' Not good news as the Liverpool captain Jordan Henderson has to be replaced by James Milner. It looks like he's done his hamstring.
14' Good interplay between Coutinho and Salah on the right wing. Salah cuts the ball backs and rolls it towards Coutinho just outside the box.
Phil fires at Cech but the ball goes wide of the goal.
Milner slowly settling in - he didn't complete the substitution for a minute or two after Henderson had to leave the field - the reds were temporarily down to ten men.
22' Mane finds Robertson at the corner of the area. The Scot whips in the cross to the back post and Firmino heads it powerfully goalbound.
Petr Cech beats it away for a corner.
24' Another header from Firmino after a quick counter attack and deep cross. This time he heads the ball down - and across the face of goal.
26' Very quick move forward for Liverpool. Mo Salah gets in a good position - flicks the ball up and it deflects nicely into the air.
Phil Coutinho has ran half the length of the pitch and heads it over Petr Cech.
Yeah - that's right - a Philippe Coutinho header!
1-0 to Liverpool
32' Roberto Firmino smashes one from just inside the box and it's marginally over the top of the crossbar and hits the support just behind the goal.
Firmino knocking on the door - wants to join his compatriot with a goal here.
End to end stuff
42' Mane getting singled out a bit for some rough treatment here. He's won a couple of free kicks from various incidents.
Approaching half time and Liverpool, resplendent in their orange kit, deservedly ahead although Arsenal ending this half with some chances of their own.
44' Reds should have done better there.
Salah and Mane both had chances. Salah's sliding shot wasn't strong enough to beat Cech and from the rebound, Mane tried an acrobatic overhead kick but it went over.
Goals gone wanting.
45' Liverpool are deep in Arsenal's area again and Salah completely misses his shot from the middle of the penalty area.
HT: Arsenal 0-1 Liverpool
Could have been many many more goals in that half. Arsenal could have done better but the reds, on another day, could have had about 5!
But Liverpool take a single goal lead into half time.
Hope we don't rue these missed chances ...should be 4 ...0 ....— Mark Wade (@mark0075) December 22, 2017
Half time sub for Arsenal - Monreal replaced by Mustafi - believed to be due to an injury picked up in that first half.
Can Liverpool hold their lead and add the goals they should have done in the first half.
48' Salah brings the ball up most of the length of the pitch, lays it off to Mane, receives it back and then has his shot saved.
Think the initial move came from an Arsenal corner.
No messing about.
52' From one end of the pitch, Salah powers up the field lays it off to Firmino who holds the ball - passes it back and then Salah curls the ball around Petr Cech, with the help of a deflection off the Arsenal defender.
54' Sanchez hits back with one almost straight away. Cross comes in from Arsenal, Joe Gomez is sleeping on the job, and Alexis Sanchez heads in to make it Arsenal 1-2 Liverpool
56' Oh dear. Granit Xhaka fires in the equaliser with his shot from 30 yards out. It was a powerful shot and flew past Mignolet who kicks the post.
58' Mezut Ozil sensationally makes it 3 for Arsenal who now lead. He runs into the area and slides the ball under the hapless Simon Mignolet.
Liverpool have conceded three times in 5 minutes. Not entirely sure what the Liverpool keeper was doing for the Xhaka equaliser. It was a decent shot yes, but he appeared to try and save it with one hand.
The third goal from Arsenal saw the defence cut open and Mignolet couldn't get down quickly enough to save the chance.
Liverpool should have had this wrapped up in the first half and despite scoring again in this half now find themselves behind.
69' Just not going right again for Sadio Mane. He makes a decent run into the area but his control is poor and Arsenal get it away.
They've got the bit between their teeth now.
70' Roberto Firmino!!!
He absolutely smashes it at the goal and it's too much for Cech to keep hold of. He gets his hands on it but it goes in.
72' Liverpool on the attack now. Is there going to be a winner in this game?
The reds force a corner.
Coutinho swings it in to Emre Can who heads it goalbounds. Petr Cech saves that one.
78' Arsenal bring on Danny Wellbeck for Alex Iwobi. Remains 3-3.
80' He's not had a good game and Mane goes off replaced by Wijnaldum.
Boos ring around the ground.
Oxlade Chamberlain on for Coutinho. 84th minute of the game.
What a story this could be.
89' And it falls to Mo Salah - but he can only fire it into the side netting.
Arsenal bring on Walcott for Sanchez.
We're going to have 4 minutes of injury time. All subs used.
Arsenal 3-3 Liverpool
Draw doesn't do much for either side. Liverpool arguably the better side but 5 minutes of madness handed Arsenal 3 goals in the middle of the half.
Liverpool did well to pick themselves up from that and get the point.
Speaking on the pitch after the final whistle James Milner insists that the reds need to close games down when they are in front.
'We need to become more boring', he says.
Next up we've got Swansea at home.
They've just got rid of their manager so, you know, expect the unexpected!